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1

At the moment of occurrence of a fragility hip fracture, men have higher mechanical properties values in comparison with women

Vale, Ana C, Aleixo, Inês P, Lúcio, Miguel, Saraiva, André, Caetano-Lopes, Joana, Rodrigues, Ana, Amaral, Pedro M, Rosa, Luís G, Monteiro, Jacinto, Fonseca, João E, Vaz, Maria F, Canhão, Helena

Journal:

BMC Musculoskeletal Disorders

Year:

2013

Language:

english

File:

PDF, 544 KB

english, 2013

2

Osteoimmunology — The hidden immune regulation of bone

Caetano-Lopes J., Canhão H., Fonseca J.E.

Journal:

Autoimmunity Reviews

Year:

2009

Language:

english

File:

PDF, 379 KB

english, 2009

3

Assessment of laboratory measurements and −308 TNFα gene promoter polymorphisms in normal bone mineral density

Helena Canhao, Joao Eurico Fonseca, Joana Caetano-Lopes, Carlota Saldanha, Mario Viana Queiroz

Journal:

Clinical Rheumatology

Year:

2008

Language:

english

File:

PDF, 154 KB

english, 2008

4

Influence of anti-tumour necrosis factor drugs, tocilizumab and methotrexate on osteoclast differentiation

Perpetuo, I, Caetano-Lopes, J, Rodrigues, A, Polido-Pereira, J, Queiroz, M V., Fonseca, J E, Canhao, H

Journal:

Annals of the Rheumatic Diseases

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

5

Fracture risk assessed by FRAX translates bone cell activity

J. Caetano-Lopes, A. Rodrigues, I. Aleixo, I.P. Perpétuo, D. Fernandes, A. Lopes, A. Faustino, A.S. Pena, J. Polido-Pereira, E. Sousa, J.C. Romeu, P.M. Amaral, J. Monteiro, M.V. Queiroz, M.F. Vaz, J.E

Journal:

Year:

2010

Language:

english

File:

PDF, 57 KB

english, 2010

6

Chronic arthritis leads to disturbances in the bone collagen network

Joana Caetano-Lopes, Ana M Nery, Helena Canhão…

Journal:

Arthritis Research & Therapy

Year:

2010

Language:

english

File:

PDF, 1.83 MB

english, 2010

7

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

Rees, Holly A., Komor, Alexis C., Yeh, Wei-Hsi, Caetano-Lopes, Joana, Warman, Matthew, Edge, Albert S. B., Liu, David R.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 849 KB

english, 2017

8

Upregulation of Inflammatory Genes and Downregulation of Sclerostin Gene Expression Are Key Elements in the Early Phase of Fragility Fracture Healing

Caetano-Lopes, Joana, Lopes, Ana, Rodrigues, Ana, Fernandes, Diana, Perpétuo, Inês P., Monjardino, Teresa, Lucas, Raquel, Monteiro, Jacinto, Konttinen, Yrjö T., Canhão, Helena, Fonseca, João E., Abdel

Journal:

Year:

2011

Language:

english

File:

PDF, 228 KB

english, 2011

9

Correction: Unique and non-redundant function of csf1r paralogues in regulation and evolution of post-embryonic development of the zebrafish

Caetano-Lopes, Joana, Henke, Katrin, Urso, Katia, Duryea, Jeffrey, Charles, Julia F., Warman, Matthew L., Harris, Matthew P.

Journal:

Development (The Company of Biologists)

Year:

2020

File:

PDF, 72 KB

2020

10

Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients

Ana Maria Rodrigues, Joana Caetano-Lopes…

Journal:

Journal of Bone and Mineral Metabolism

Year:

2012

Language:

english

File:

PDF, 201 KB

english, 2012

11

Clcn7 F318L/+ as a new mouse model of Albers-Schönberg disease

Caetano-Lopes, J., Lessard, S.G., Hann, S., Espinoza, K., Kang, K.S., Lim, K.E., Horan, D.J., Noonan, H.R., Hu, D., Baron, R., Robling, A.G., Warman, M.L.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.62 MB

english, 2017

12

Low serum levels of DKK2 predict incident low-impact fracture in older women

Rodrigues, Ana M., Eusébio, Mónica, Rodrigues, Ana B., Caetano-Lopes, Joana, Lopes, Inês P., Lopes, Ana, Mendes, Jbmge M., Coelho, Pedro Simões, Fonseca, João Eurico, Branco, Jaime C., Canhão, Helena

Journal:

Year:

2019

File:

PDF, 971 KB

2019

13

THU0393 Estimated Glomerular Filtration Rate is Associated with Bone Fragility in the Elderly

Gonçalves, M. J., Rodrigues, A., Caetano-Lopes, J., Lopes, A., Vidal, B., Raquel, E., Sarmento, M., Canhão, H., Fonseca, J. E., Vaz, F., Monteiro, J.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 251 KB

english, 2013

14

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis

Perpétuo, Inês P., Caetano-Lopes, Joana, Rodrigues, Ana Maria, Campanilho-Marques, Raquel, Ponte, Cristina, Canhão, Helena, Ainola, Mari, Fonseca, João E.

Journal:

BioMed Research International

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

15

Influence of TNF blockers, tocilizumab and methotrexate on osteoclast differentiation in rheumatoid arthritis patients

I.P. Perpétuo, J. Caetano-Lopes, A. Rodrigues, J. Polido-Pereira, M. Viana Queiroz, J.E. Fonseca, H. Canhão

Journal:

Year:

2010

Language:

english

File:

PDF, 54 KB

english, 2010

16

Gene expression on osteoclast precursors from rheumatoid arthritis patients

I.P. Perpétuo, J. Caetano-Lopes, J. Polido-Pereira, J.A. Pereira da Silva, J.E. Fonseca, H. Canhão

Journal:

Year:

2011

Language:

english

File:

PDF, 124 KB

english, 2011

17

Rheumatoid Arthritis Bone Fragility Is Associated With Upregulation of IL17 and DKK1 Gene Expression

Joana Caetano-Lopes, Ana Rodrigues, Ana Lopes…

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

18

Bone cell activity influences bone fragility and fracture risk

Caetano-Lopes, J, Aleixo, I, Rodrigues, A, Perpetuo, I P, Fernandes, D, Lopes, A, Pena, A, Faustino, A, Vale, M, Amaral, P M, Monteiro, J, Vaz, M F, Canhao, H, Fonseca, J E

Journal:

Annals of the Rheumatic Diseases

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

19

Micro-computed tomography and compressive characterization of trabecular bone

Vale, A.Catarina, Pereira, M.F.C., Maurício, A., Amaral, P., Rosa, L.G., Lopes, A., Rodrigues, A., Caetano-Lopes, J., Vidal, B., Monteiro, J., Fonseca, J.E., Canhão, H., Vaz, M.Fátima

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

20

Ankylosing Spondylitis Susceptibility and Severity-Contribution of TNF Gene Promoter Polymorphisms at Positions -238 and -308

Sousa, Elsa, Caetano-Lopes, Joana, Pinto, Patrícia, Pimentel, Fernando, Teles, José, Canhão, Helena, Rodrigues, Ana, Resende, Catarina, Mourão, Ana Filipa, Ribeiro, Célia, Pinto, Teresa Laura, Rosa, C

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 148 KB

english, 2009

21

Tumor Necrosis Factor- -308 Genotypes Influence Inflammatory Activity and TNF- Serum Concentrations in Children with Juvenile Idiopathic Arthritis

Mourao, A. F., Caetano-Lopes, J., Costa, P., Canhao, H., Santos, M. J., Pinto, P., Brito, I., Nicola, P., Cavaleiro, J., Teles, J., Jose, A. S., Gomes, M., Branco, J., da Costa, J. T., Pedro, J. G., d

Journal:

The Journal of Rheumatology

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

22

A4.2 Chronic kidney disease associates with worse trabecular mechanical performance in hip osteoarthritis patients independently of bone mineral density

Sepriano, A., Goncalves, M. J., Rodrigues, A., Lopes, A., Caetano-Lopes, J., Fonseca, J. E., Canhao, H.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 69 KB

english, 2014

23

A4.3 Differences of bone WNT regulators expression between fragility fractures and osteoarthritis patients

Rodrigues, A., Caetano-Lopes, J., Oliveira, V., Vidal, B., Goncalves, M., Sepriano, A., Sarmento, M., Monteiro, J., Fonseca, J., Canhao, H.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 68 KB

english, 2014

24

Biomechanical effects of inflammatory diseases on bone-rheumatoid arthritis as a paradigm

S. Abdulghani, J. Caetano-Lopes, H. Canhão, J.E. Fonseca

Journal:

Autoimmunity Reviews

Year:

2009

Language:

english

File:

PDF, 329 KB

english, 2009

25

Negative correlation between osteocalcin serum levels and bone mechanical properties

A. Rodrigues, I.P. Perpétuo, J. Caetano-Lopes, I. Aleixo, A. Pena, A. Faustino, J. Polido-Pereira, E. Sousa, J. Romeu, P. Amaral, J. Monteiro, M.V. Queiroz, M.F. Vaz, J.E. Fonseca, H. Canhão

Journal:

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

26

Low osteocalcin/collagen type I bone gene expression ratio is associated with hip fragility fractures

Ana M. Rodrigues, Joana Caetano-Lopes, Ana C. Vale, Bruno Vidal, Ana Lopes, Inês Aleixo, Joaquim Polido-Pereira, Alexandre Sepriano, Inês P. Perpétuo, Jacinto Monteiro, Maria F. Vaz, João E. Fonseca,

Journal:

Year:

2012

Language:

english

File:

PDF, 789 KB

english, 2012

27

A4.5 Procollagen type 1 amino-terminal propeptide is negatively associated with bone stiffness in subpopulations of patients submitted to hip replacement surgery

Goncalves, M., Sepriano, A., Rodrigues, A., Lopes, A., Caetano-Lopes, J., Fonseca, J., Canhao, H.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 70 KB

english, 2014

28

AB0955 Apolipoprotein e and undercaboxylated osteocalcin are associated with bone fragility but not with bone mineral density in osteoarthritis patients

Rodrigues, A.M., Caetano-Lopes, J., Lopes, A., Vale, A.C., Pena, A.S., Faustino, A., Sepriano, A., Vidal, B., Romeu, J.C., Pereira da Silva, J.A., Monteiro, J., Vaz, M.F., Fonseca, J.E., Canhão, H.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

File:

PDF, 43 KB

2013

29

Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis

Perpétuo, Inês Pedro, Caetano-Lopes, Joana, Rodrigues, Ana Maria, Campanilho-Marques, Raquel, Ponte, Cristina, Canhão, Helena, Ainola, Mari, Fonseca, João Eurico

Journal:

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

30

Tumour necrosis factor antagonists and tocilizumab have a higher impact on rheumatoid arthritis osteoclastogenic stimuli than methotrexate

Perpetuo, I, Fernandes, D, Cascao, R, Moura, R, Caetano-Lopes, J, Rodrigues, A, Polido-Pereira, J, Viana Queiroz, M, Fonseca, J E, Canhao, H

Journal:

Annals of the Rheumatic Diseases

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010

31

AB0162 Rank Expression is Reduced in Circulating Monocytes from Ankylosing Spondylitis Patients

Perpétuo, I.P., Caetano-Lopes, J., Vieira-Sousa, E., Campanilho-Marques, R., Ponte, C., Canhão, H., Ainola, M., Fonseca, J.E.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 72 KB

english, 2014

32

Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors

Perpétuo, Inês P., Caetano-Lopes, Joana, Vieira-Sousa, Elsa, Campanilho-Marques, Raquel, Ponte, Cristina, Canhão, Helena, Ainola, Mari, Fonseca, João E.

Journal:

Frontiers in Medicine

Year:

2017

Language:

english

File:

PDF, 3.57 MB

english, 2017

33

Low serum levels of DKK2 predict incident low-impact fracture in older women

Rodrigues, Ana M., Eusébio, Mónica, Rodrigues, Ana B., Caetano-Lopes, Joana, Lopes, Inês P., Lopes, Ana, Mendes, Jbmge M., Coelho, Pedro Simões, Fonseca, João Eurico, Branco, Jaime C., Canhão, Helena

Journal:

Year:

2019

Language:

english

File:

PDF, 971 KB

english, 2019

34

Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing

J. Caetano-Lopes, A. Lopes, A. Rodrigues, D. Fernandes, I.P. Perpétuo, J. Monteiro, H. Canhão, J.E. Fonseca

Journal:

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

35

Upregulation of inflammatory genes and downregulation of sclerostin are key elements for fracture healing

J Caetano-Lopes, A Lopes, A Rodrigues, D Fernandes…

Journal:

Journal of Translational Medicine

Year:

2010

Language:

english

File:

PDF, 119 KB

english, 2010

36

Lymphotoxin- 252 A>G Polymorphism: A Link Between Disease Susceptibility and Dyslipidemia in Rheumatoid Arthritis?

SANTOS, M. J., FERNANDES, D., CAETANO-LOPES, J., PERPETUO, I. P., VIDAL, B., CANHAO, H., FONSECA, J. E.

Journal:

The Journal of Rheumatology

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

37

THU0034 Rheumatoid arthritis bone fragility is associated with increased DKK1 expression and disturbances in the bone turnover regulating genes

Caetano-Lopes, J., Rodrigues, A., Lopes, A., Vale, A.C., Monteiro, J., Vaz, M.F., Nazarian, A., Canhão, H., Fonseca, J.E.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 88 KB

english, 2013

38

TNF promoter -308 G>A and LTA 252 A>G polymorphisms in Portuguese patients with systemic lupus erythematosus

Santos, Maria José, Carmona-Fernandes, Diana, Caetano-Lopes, Joana, Perpétuo, Inês P., Vidal, Bruno, Capela, Susana, Canas da Silva, José, Fonseca, João Eurico

Journal:

Rheumatology International

Year:

2012

Language:

english

File:

PDF, 301 KB

english, 2012

39

Absolute risk of fracture calculated by FRAX reflects Bone mechanical properties

A. Rodrigues, J. Caetano-Lopes, I.P. Perpétuo, I. Aleixo, A.S. Pena, A. Faustino, J. Polido-Pereira, E. Sousa, J.C. Romeu, P.M. Amaral, J. Monteiro, M.V. Queiroz, M.F. Vaz, J.E. Fonseca, H. Canhão

Journal:

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

40

Rheumatoid arthritis bone fragility is associated with increased DKK1 expression and disturbances in the bone turnover regulating genes

J. Caetano-Lopes⁎, A.M. Rodrigues, A. Lopes, A.C. Vale, B. Vidal, I.P. Perpétuo, M.F. Vaz, A. Nazarian, J.E. Fonseca, H. Canhão

Journal:

Year:

2012

Language:

english

File:

PDF, 72 KB

english, 2012

41

The skeletal phenotype of Achondrogenesis type 1A is caused exclusively by cartilage defects

Bird, Ian M., Kim, Susie H., Schweppe, Devin K., Caetano-Lopes, Joana, Robling, Alexander G., Charles, Julia F., Gygi, Steven P., Warman, Matthew L., Smits, Patrick J.

Journal:

Development (The Company of Biologists)

Year:

2017

Language:

english

File:

PDF, 5.67 MB

english, 2017

42

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals

Bettencourt, B. F., Rocha, F. L., Alves, H., Amorim, R., Caetano-Lopes, J., Vieira-Sousa, E., Pimentel-Santos, F., Lima, M., Porto, G., Branco, J. C., Fonseca, J. E., Bruges-Armas, J.

Journal:

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

43

Rheumatoid arthritis is associated with increased DKK1 expression and disturbances in the bone turnover regulating genes

Joana Caetano-Lopes, Ana Rodrigues, Ana Lopes, Ana C Vale, Michael A Pitts-Kiefer, Bruno Vidal, Inês P Perpétuo, Jacinto Monteiro, Yrjö T Konttinen, Maria F Vaz, Ara Nazarian, Helena Canhão, João E Fo

Journal:

Journal of Translational Medicine

Year:

2011

Language:

english

File:

PDF, 71 KB

english, 2011

44

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, 14–17 June, 2017 - ()] Abstracts Accepted for Publication - AB0097 Methotrexate and low dose prednisolone downregulate osteoclast function in monocytes from early rheumatoid arthritis patients

Perpétuo, IP, Caetano-Lopes, J, Rodrigues, AM, Campanilho- Marques, R, Ponte, C, Canhão, H, Ainola, M, Fonseca, JE

Language:

english

File:

PDF, 70 KB

english

45

Apolipoprotein E and undercaboxylated osteocalcin are associated with bone fragility but not with bone mineral density in osteoarthritis patients

Ana Rodrigues, Joana Caetano-Lopes, Ana Lopes, Ana C Vale, Inês Aleixo, Inês P Perpétuo, Ana S Pena, Alexandra Faustino, Alexandre Sepriano, Joaquim Polido-Pereira, Elsa Vieira-Sousa, Bruno Vidal, Jos

Journal:

Journal of Translational Medicine

Year:

2011

Language:

english

File:

PDF, 86 KB

english, 2011

46

An analysis of joint replacement in patients with systemic lupus erythematosus

Mourao, A., Amaral, M., Caetano-Lopes, J., Isenberg, D.

Journal:

Year:

2009

Language:

english

File:

PDF, 78 KB

english, 2009

47

Alterations on peripheral blood B-cell subpopulations in very early arthritis patients

Moura, R. A., Weinmann, P., Pereira, P. A., Caetano-Lopes, J., Canhao, H., Sousa, E., Mourao, A. F., Rodrigues, A. M., Queiroz, M. V., Souto-Carneiro, M. M., Graca, L., Fonseca, J. E.

Journal:

Year:

2010

Language:

english

File:

PDF, 573 KB

english, 2010

48

A4.21 Effect of TNF blocking therapy on osteoclasts from ankylosing spondylitis patients

Perpétuo, IP, Raposeiro, R, Caetano-Lopes, J, Vieira-Sousa, E, Campanilho-Marques, R, Ponte, C, Canhão, H, Ainola, M, Fonseca, JE

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 82 KB

english, 2015

49

A2.1 Rank expression is reduced in circulating monocytes from ankylosing spondylitis patients

Perpétuo, I P, Caetano-Lopes, J, Vieira-Sousa, E, Campanilho-Marques, R, Ponte, C, Canhão, H, Ainola, M, Fonseca, J E

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 82 KB

english, 2014

50

FRI0192 Effect of TNF Blocking Therapy on Osteoclasts from Ankylosing Spondylitis Patients

Perpétuo, I.P., Raposeiro, R., Caetano-Lopes, J., Vieira-Sousa, E., Campanilho-Marques, R., Ponte, C., Canhão, H., Ainola, M., Fonseca, J.E.

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 87 KB

english, 2015

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